Analysis of Connectivity of Gray Matter Regions Using DTI and Graph Theory

Amy Kuceyeski¹, Ashish Raj¹

The connectivity of gray matter regions in the brain via white matter tracts has recently become an area of wide interest due to the advances in imaging techniques that measure structural connections via white matter (DTI. The information that can be extracted from this modality has not yet been harvested fully due to its relative novelty; however some studies have proven its potential. We propose a computational methodology that utilizes DTI and structural images of the brain, graph theory, and clustering algorithms to explore regions of high connectivity and importance to overall connectivity in normal brains.