Abstract #1667

Diffusion MRI and Anatomical Tracer Tractography of Association Pathways in the Same Brain

Jennifer Campbell¹, Ilana R. Leppert¹, Stephen Frey², Michael Petrides², G. Bruce Pike¹

¹McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada; ²Cognitive Neuroscience Unit, Montreal Neurological Institute, McGill University

Reliable in vivo diffusion MRI fibre tractography, particularly in association pathways, remains a difficult task due to a mismatch between the tract size and the image resolution achievable in a reasonable scan time. The objective of this study was to perform both diffusion MRI tractography and traditional tracer injection tract tracing in the association pathways of the same rhesus macaque monkey. Evaluation of diffusion MRI tract tracing in these association pathways can give us insight into its feasibility for mapping subtle connectivity in the human brain.