Peter Gibbs1, Martin D. Pickles1,
Lindsay W. Turnbull1
1Centre for MR Investigations,
Recent
work has demonstrated that it is technically possible to acquire DWI data
with low b-values to quantify the
perfusive fraction of the ADC decay curve via bi-exponential modelling.
This work seeks to assess the repeatability of such modelling and the
dependence on accurate b-value
implementation by system manufacturers. A repeatability of 21% for
mono-exponential fitting indicates its efficacy for monitoring treatment
induced changes. Bi-exponential fitting is found to be less repeatable,
especially the perfusive fraction parameter.