Ezequiel
Alejandro Farrher1, Erasmo Batta1, Yuliya Kupriyanova1,
Oleg Posnansky1, Farida Grinberg1, N Jon Shah1,2
1Medical Imaging Physics, Institute of
Neuroscience and Medicine 4 ,
Forschungszentrum Juelich GmbH, Juelich, Germany; 2Department of
Neurology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany
Diffusion
Tensor Imaging (DTI) provides access to fibre pathways and structural
integrity in the white matter and finds important applications in the
clinical practice. Many advanced techniques have been recently suggested for
the reconstruction of the diffusion orientation distribution function with an
enhanced angular resolution (HARDI). Examination of the sensitivity of the
proposed diffusion indices to the underlying microstructure requires a
development of the model systems with deliberately tailored properties. The
aim of this work was to construct artificial phantoms that are characteristic
of sufficiently strong diffusion anisotropy and are suitable for the
validation of the analytical models.