Anh Tu
Van1, Dimitrios C. Karampinos2, Bradley P. Sutton3,4
1Electrical and Computer Engineering, University
of Illinois, Urbana, IL, United States; 2Radiology and Biomedical
Imaging, University of California, San Francisco, CA, United States; 3Bioengineering,
University of Illinois, Urbana, IL, United States; 4Beckman
Institute, University of Illinois, Urbana, IL, United States
High
isotropic resolution diffusion-weighted imaging is required in order to
reduce partial volume effects in the estimation of diffusion metrics. In the
present work, a novel high resolution 3D spin echo diffusion-weighted acquisition
strategy is proposed. The acquisition is time efficient, fairly immune to
gross motion and pulsation effects, and has a simple diffusion-weighted
signal model. High quality, high resolution (1.88 x 1.88 x 1.88 mm3)
diffusion-weighted images, FA maps, color-coded FA maps (13 directions) with
whole brain coverage were achieved within a reasonable scan time.