Yohan van de
Looij1,2, Nicolas Kunz1,2, Petra S. Hppi1,
Rolf Gruetter2,3, Stphane V. Sizonenko1
1Division of Child Growth &
Development, Department of Pediatrics, University of Geneva, Geneva,
Switzerland; 2Laboratory for Functional and Metabolic Imaging,
Ecole Polytechnique Fdrale de Lausanne, Lausanne, Switzerland; 3Department
of Radiology, University of Geneva and Lausanne, Geneva and Lausanne,
Switzerland
A
large number of small bore systems propose implemented sequences making easy
the use of DTI but the choice of sequence parameters can have a huge impact
on the derived tensor quantifications. The aim of this work was to study the
influence of diffusion time (td) and brain microstructures on diffusion derived
parameters in the rat brain at 9.4T. 3 repeated DTEPI images (4 shots) were
performed with td = 10, 25 and 39 ms respectively. This study shows in white
and gray matter a dependence of diffusion derived parameters on td from 10 ms
to 25 ms.