Farida
Grinberg1, Ezequiel A. Farrher1, Joachim Kaffanke1,
Ana-Maria Oros-Peusquens1, N. Jon Jon Shah1,2
1Medical Imaging Physics, Institute of
Neuroscience and Medicine 4, Forschungszentrum Juelich GmbH, Juelich,
Germany; 2Department of Neurology, Faculty of Medicine, RWTH
Aachen University, Aachen, Germany
Diffusion
MRI permits non-invasive probing of tissue microstructure and function and
provides invaluable information in brain diagnostics. Conventional methods,
however, are designed to retrieve only the average diffusion characteristics
and tend to ignore deviations from simple Gaussian behaviour. Recently,
increasing efforts have been dedicated to the development of the advanced
approaches capable of capturing more detailed information on the propagation
mechanisms. In this work, we report an in vivo diffusion study of the brain
based on a detailed analysis of the attenuation patterns. New quantitative
indices are suggested as map parameters and their potential use with respect
to studies of the brain is discussed.