Jonathan C. Sharp1, Donghui Yin2,
Boguslaw Tomanek1, Scott B. King2
1Institute for Biodiagnostics (West),
National Research Council of
Imaging
without B0-gradients by the TRASE method is based on echo trains with
refocusing pulses produced by RF phase gradient fields. K-space evolution
occurs between successive echoes. The use of phase gradients means that pulse
phases vary spatially. Also |B1| inhomogeneity, causing flip-angle errors, is
always present. Both effects combine to result in each location in the sample
experiencing a different pulse sequence, which results in a
position-dependent point-spread-function (PSF). We examine how the relationships between
sequence design, coil design and flip angle calibration can be used to
maximize the sample volume offering a good PSF.