Gunther Schneider1, Mieczyslaw Pasowicz2,
Josef Vymazal3, Zdenek Seidl4, Manuela Aschauer5,
Deniz Bilecen6, Roberto Iezzi7, Claudio E M Ballarati8
1Radiology, University Hospital
Hamburg, Hamburg/Saar, Germany; 2Diagnostics and Rehabilitation,
John Paul II Hospital, Krakow, Poland; 3Radiology, Na Homolce
Hospital, Prague, Czech Republic; 4Radiology, Lkarsk Fakulta
Neurologicka Klinika, Prague, Czech Republic; 5Medical University
of Graz, Graz, Austria; 6Radiology, University Hospital Basel,
Switzerland; 7Radiology, Universit G. D'Annunzio, Chieti, Italy; 8Radiology,
Hospital Valduce, Como, Italy
In
a prospective comparison of the efficacy and safety of gadobenate dimeglumine
vs the intravascular blood pool agent gadofosveset trisodium for
contrast-enhanced MR angiography (CE-MRA) of the renal arteries in 38
subjects, blinded experts consistently found first-pass CE-MRA after
gadobenate dimeglumine to be superior to CE-MRA after gadofosveset in terms
of sensitivity, specificity, accuracy, PPV, and NPV. Steady state images
obtained following gadofosveset administration provided no additional
diagnostic benefit in this study.