Abstract #1356

Evaluation of the Coherence of Local Indices of Aortic Stiffness Calculated from Magnetic Resonance Data Using a Theoretical Model Derived from the Moens-Korteweg Equation

Anas Dogui¹, Nadjia Kachenoura², Alain De Cesare², Muriel Lefort¹, Mourad Bensalah^1,3, Alain Herment¹, Boutouyrie Pierre^4,5, Elie Mousseaux^1,6

¹INSERM U678 ,UPMC, Paris, France; ²INSERM U678,UPMC, Paris, France; ³Radiology department, APHP, European Hospital Georges Pompidou,, Paris, France; ⁴INSERM U970, Paris, France; ⁵Pharmacology department, APHP, European Hospital Georges Pompidou, Paris, France; ⁶Radiology department, APHP, European Hospital Georges Pompidou, Paris, France

Aortic stiffness indices such as the local aortic deformability (AD) and the regional aortic pulse wave velocity (PWV) were assessed directly and non-invasively from morphological and hemodynamic magnetic resonance data on 40 subjects. The consistency of these indices was well described by a theoretical model derived from the Moens-Korteweg equation. A global aortic deformability (ADe) was estimated from PWV and carotid pulse pressure using the theoretical model and gave a similar description of stiffness of the ascending aorta as the local AD.