Abstract #1345
Quantification
of Pre-Systolic Left Ventricular 4D Blood Flow Organization in Normal and
Failing Hearts
Jonatan Eriksson1, Petter Dyverfeldt1,
Jan Engvall1, Ann F. Bolger2, Tino Ebbers1,
Carl-Johan Carlhll1
1Linkping University and Center for
Medical Image Science and Visualization (CMIV), Linkping, Sweden; 2University
of California San Francisco, San Francisco, CA, United States
Multidimensional
patterns of intracardiac blood flow remain poorly characterized in health and
disease. An extended pathline based left ventricular (LV) 4D blood flow quantification approach
is presented. Three-directional, three-dimensional cine phase-contrast MRI
data was acquired in healthy subjects and patients with idiopathic dilated
cardiomyopathy and analyzed for assessment of the pre-systolic LV blood flow
organization, in order to evaluate the preparation of different flow
components for systolic outflow. Quantification of pre-systolic orientation
may reflect an aspect of ventricular systolic efficiency that is impacted by
flow-specific organization inside the diastolic ventricle.
