Gyda S. Karlsdottir1, Sigurdur Sigurdsson1,
Thor Aspelund1, Gudny Eiriksdottir1, Jie J. Cao2,
Lenor Launer3, Tamara B. Harris3, Robert Detrano4,
Andrew Arai5, Vilmundur Gudnason6
1Icelandic Heart Association Research
Institute, Kopavogur, Iceland; 2National Heart, Lung and Blood
Institute, Bethesda, United States; 3IRP, National Institute on
Aging, Bethesda, United States; 4University of California Irvine,,
Irvine, United States; 5IRP, National Heart, Lung and Blood
Institute, Bethesda, United States; 6Icelandic Heart Association
Research Institute, Kopavogur, Iceland
Purpose
of our study was to investigate the association of the extent of MI localized
by gadolinium enhanced MRI, and the quantity of calcium in the coronary
arteries detected with CT. Of the 674 subject, 21% had evidence of MI.
Subjects with MI in all three coronary distributions had higher coronary
calcium score (CCS), compared to those with MI in only one. Those with only
one or two infarcted segments had significantly lower CCS than those with
infarct in three or more segments. The relationship between the extent of MI
and quantity of coronary calcium is significant and strong.