Venkatesh Mani1, Simonette T. Sawit2,
Claudia Calcagno1, Cynara Maceda2, Colin Moncrieff1,
Zahi Adel Fayad1, Jacqueline Moline3, MaryAnn
McLaughlin2
1Radiology, Mount Sinai School of
Medicine, New York, NY, United States; 2Cardiology, Mount Sinai
School of Medicine, New York, NY, United States; 3Preventive
Medicine, Mount Sinai School of Medicine, New York, NY, United States
Exposure
to particulate matter (PM) has been associated with adverse health effects
leading to increased morbidity and mortality. Dynamic contrast enhanced (DCE)
MRI and peripheral arterial tonometry (PAT) may potentially be used to
evaluate differences in atherosclerosis in patients with high and low PM
exposure. There was correlation between DCE-MRI measures and endothelial
function measured by PAT. Despite NO significant differences between groups
in patient characteristics, and vessel wall morphometrics, high exposure
group had significantly lower DCE MRI measures. We conclude that DCE-MRI may be used to
evaluate differences in atherosclerosis due to different levels of PM
exposure.