Xubin Li1,2, Huidong Gu1,
Hongqing Feng1, Xiangke Du2, Bensheng Qiu1,
Xiaoming Yang1
1Image-Guided Bio-Molecular
Intervention Researchers, Department of Radiology; Institute for Stem Cel,
University of Washington School of Medicine, Seattle, WA, United States; 2Radiology,
Peking University People's Hospital, Beijing, China
The
aim of this study was to explore the possibility of generating
high-resolution MR images of atherosclerotic aortic walls/plaques of mice
using a clinical 3.0 Tesla MR scanner. This study demonstrates that clinical
3.0T MR scanners can be used for high-resolution imaging of atherosclerotic
vascular walls and lesions in mice, which is guaranteed with a specific mouse
RF coil, an effective ECG-gating system, and a BB-MRI sequence.