Hsiao-Ying Wey1,2, Jinqi Li1, M.
Michelle Leland3, Lisa Jones3, C Akos Szabo4,
John W. Roby1, James T. Scribner1,2, Ghzawan M. Kroma2,
Peter T. Fox1, Timothy Q. Duong1,2
1Research Imaging Institute, UT Health
Science Center at San Antonio, San Antonio, TX, United States; 2Radiology,
UT Health Science Center at San Antonio, San Antonio, TX, United States; 3Laboratory
Animal Resources, UT Health Science Center at San Antonio, San Antonio, TX,
United States; 4Neurology, UT Health Science Center at San
Antonio, San Antonio, TX, United States
This
study reports a robust anesthetized baboon model for BOLD fMRI studies on a
clinical 3T human MRI scanner. BOLD fMRI of visual and somatosensory/motor
stimulations in anesthetized baboons were investigated. Comparisons of BOLD
fMRI sensitivity were made between isoflurane and ketamine anesthetics with
and without paralytics. To our knowledge, this is the first report on baboon
BOLD fMRI of visual and somatosensory/motor.