Andy Paul Salzwedel1, Matt Mauck2,
James Kuchenbecker3, Chris Pawela1, James Hyde1,
Maureen Neitz3, Jay Neitz3
1Biophysics, Medical College of
Wisconsin, Milwaukee, WI, United States; 2Department of
Ophthalmology, Cell Biology, Neurobiology, and Anatomy, Medical College of
Wisconsin, Milwaukee, WI, United States; 3Ophthalmology,
University of Washington, Seattle, WA, United States
In
a comparative study, the visual pathways of two different animal models
(rodent vs primate) were probed using high field strength (9.4T) fMRI. The
primary goal of this research was to assay the color vision systems of these
two species in hope of demonstrating the evolutionary homology thereof. Here
we present several techniques that combine to form a unique overall method
for probing this pathway; pharmacological intervention (AP4), precession fMRI
compatible LED based stimuli, and intra-brain controls.