Toshiharu Nakai1, Makoto Miyakoshi1,
Epifanio Bagarinao1, Masaki Yoshida2, Chikako Nakai3,
Kayako Matsuo4
1Functional Brain Imaging Lab, National
Center for Geriatrics and Gerontology, Ohbu, Aichi, Japan; 2Ophthalmology,
The Jikei University, Tokyo, Japan; 3School of Health Sciences,
Toyoshashi Sozo University, Toyohashi, Aichi; 4Psychology,
National Taiwan University, Taipei, Taiwan
We
evaluated the effect task demand for visual processing on the age-related
change of the brain activation in healthy subjects. In the elderly subjects,
the % HRF in V1 was reduced by the flickering checkerboard stimuli. By a
visuo-motor translation task the % HRF in BA19/7/39 was increased in the
elderly, while no significant difference of % HRF was detected between the
two age groups in V1. HRF analysis suggested that age-related change of % HRF
may depend on the existence of neuronal network to compensate the potential
functional decline according to aging.