Abstract #1134

Calibrated FMRI During a Cognitive Stroop Task in the Aging Brain

Rafat Saeed Mohtasib^1,2, Vanessa Sluming^1,2, Laura Parkes^1,3

¹Magnetic Resonance and Image Analysis Research Centre (MARIARC), The University of Liverpool, Liverpool, United Kingdom; ²Medical Imaging Department, The University of Liverpool, United Kingdom; ³Imaging Science and Biomedical Engineering, School of Cancer and Imaging Sciences, The University of Manchester, United Kingdom

Calibrated fMRI is a new technique that allows quantitative estimates of the relative changes in cerebral metabolic rate of oxygen (CMRO2) and cerebral blood flow (CBF) that accompany neural activation. In this research we extend our previous work to study changes in neurovascular coupling over an age range during a cognitive Stroop task.