Bernd
Michael Mller-Bierl1, Verena Pawlak2, Jason Kerr2,
Kamil Ugurbil3, Kamil Uludag1
1MRC, Max-Planck Institute for
Biological Cybernetics, Tbingen, Germany; 2NWG, Max-Planck
Institute for Biological Cybernetics, Tbingen, Germany; 3Center
for Magnetic Resonance Research, University of Minnesota, Minnesota,
Minneapolis, United States
We
present a realistic vascular model based on Monte-Carlo modeling of diffusion
and the finite element method to compute the background magnetic field of
partly oxygenated finite venules exposed to up to 16.4 T. Our data show that
the realistic vasculature data set is necessary to account for the effects
due to finite-sized vessels. The venule data herein stems from 2 photon
microscopy of the rat brain. Results show that the infinite vessel model is
prone to error so that the use of realistic vascular data sets is necessary
to get precise results. However, for a better understanding more realistic
vascular data sets should be examined in future work.