Marius Moisa1,
Rolf Pohmann1, Hartwig Roman Siebner2, Axel Thielscher1
1Max Planck Institute for Biological
Cybernetics, Tbingen, BW, Germany; 2Danish Research Centre for
Magnetic Resonance, Copenhagen University Hospital Hvidovre, Copenhagen,
Denmark
We
have recently demonstrated the technical feasibility and the potential advantages
of combining transcranial magnetic stimulation (TMS) with continuous arterial
spin labeling (CASL) imaging. Here, we use this novel approach to assess the
effects of repetitive TMS applied to the left dorsal premotor cortex (PMd) on
rCBF (regional cerebral blood flow) during different motor states. The
state-dependent effects of left PMd rTMS on rCBF, is in concordance with
previous results using BOLD imaging and a different task. As a next step, we
will analyze the time dependence of the observed TMS effects across the
different experimental blocks of one run.