Seo-Hyun Lee1, Chang-Ki Kang1,
Chan-A Park1, Young-Bo Kim1, Zang-Hee Cho1,2
1Neuroscience Research Institute,
Gachon University of Medicine and Science, Incheon, Korea, Republic of; 2Department
of Radiological Sciences, University of California, Irvine, Irvine, CA,
United States
MR
venography using susceptibility weighted imaging (SWI) has been utilized for
the study of venous morphology and the venous vasculature in disease states.
However, SWI has poor intrinsic temporal resolution, thus it is not able to
provide information on high temporal dynamic changes within a few seconds
that occur during neural stimulation. In this paper, we proposed a technique,
which we labeled functional MR venography (fMRV), to investigate the venous
dynamic response to external stimulation using 7T MRI. The presented result
suggests that this technique may provide important, more precise information
regarding the venous response and its role in the overall hemodynamic
response to neural activity with high spatial (0.5 isotropic) and temporal (3
seconds) resolution.