Abstract #1005

Binomial Sequence for Selective Quadrupolar 23Na in Vitro and in Vivo NMR and MRI

Christoffer Laustsen^1,2, Steffen Ringaard¹, Michael Pedersen¹, Niels Christian Nielsen,^2,3

¹Klinisk Institut, The MR Research Centre, Aarhus University, Aarhus, Denmark; ²iNano, Aarhus University, Aarhus, Denmark; ³inSPIN, Aarhus University, Aarhus, Denmark

The ion potential has a crucial role en cell metabolism, and is therefore a potential diagnostic target for various diseases. The purpose of this study was to investigate the use of the well known water suppression techniques: binomial sequences, for sodium NMR and MRI. We show that the binomial sequences posses many interesting features for different applications for S=3/2 nuclei, mainly that the central peak and the satellite peaks is either excited or suppressed independently, the other feature is the QJR regime, where only the central peak of a given quadrupolar interaction is observed.