Abstract #0996

in Vivo Molecular Imaging of Angiogenesis in Murine Urogenital Organs with Targeted Perfluorocarbon Nanoparticles and 19F ultrafast Turbo Spectroscopic Imaging (F-uTSI)

Muhammed Yildirim^1,2, Anke De Vries², Monique Berben¹, Caren van Cammen³, Klaas Nicolay², Holger Gruell^1,2, Rolf Lamerichs¹

¹Philips Research, Eindhoven, Netherlands; ²Biomedical NMR, Faculty of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands; ³Maastricht University, Maastricht, Netherlands

MR molecular imaging method based on 19F targeted nanoparticles and novel imaging sequences promises potential use in examining angiogeneic processes taking place in the ovaries and the endometrium in situ. Angiogenesis in the urogenital organ of the femal plays a vital role endometriosis, endoendometrial cancer and infertility.