Chin-Yu Lu1,
Yi-Ru Lin2, Stefan Posse3,4, Shang-Yueh Tsai5
1Biomedical Engineering, National
Taiwan University of Science and Technology, Taipei, Taiwan; 2Eletronic
Engineering, National Taiwan University of Science and Technology, Taipei,
Taiwan; 3Department of Neurology, University of New Mexico School
of Medicine, Albuquerque, Albuquerque, New Mexico 87131, United States; 4Electrical
and Computer Engineering Department, University of New Mexico, Albuquerque,
NM, United States; 5Electrical Engineering, Chang Gung University,
Taoyuan, Taiwan
Previous
dsrPEPSI study which measured glutamate (Glu) shown the feasibility to reduce
scan time from 16 mins to 1min. However, as scan time reduced, the SNR
decreased and poor spectra qualities were observed. This study conducted to
investigate and optimize the spectra quality versus scan time by tuning the
arrangement of radial trajectories and TEs. From our result, 4-fold dsrPEPSI
is feasible to acquire Glu at a 3T system while maintaining spectral quality.
And the scan time was 4 minutes, which was a reasonable length for clinical
use.