Implementation and Validation of Localized Constant-Time PRESS on a 7T MRI/MRS Scanner

Bhaskaran David Prakash¹, Loyola D'Silva¹, Kishore Bhakoo¹, David Townsend¹, S. Sendhil Velan¹

We have implemented and validated the LCT-PRESS technique in healthy rat brain. This sequence clearly demonstrates superior resolution and permits reliable detection of several brain metabolites that overlap in conventional techniques. The LCT-PRESS sequence performs this separation due to its incorporation of constant-time evolution, resulting in spin-spin decoupling along the F1 dimension.