Martin
Meyerspeer1,2, Ewald Unger1, Thomas Mandl1,2,
Tom Scheenen3, Graham J. Kemp4, Ewald Moser, 2
1Center for Biomedical Technology and
Physics, Vienna Medical University, Vienna, Austria; 2High Field
MR Centre of Excellence, Vienna Medical University, Vienna, Austria; 3Dpt.
of Radiology, Radboud University, Nijmegen, Netherlands; 4School
of Clinical Science, Faculty of Medicine, University of Liverpool, Liverpool,
United Kingdom
The
effect of localised versus non-localised 31P MRS on data acquired from
aerobically exercising human gastrocnemius muscle is studied at ultra hight
field. For localisation, a short TE
single voxel spectroscopy MR sequence comprising adiabatic refocussing which
allows high temporal resolution is used.
From a series of exercise bouts of equal intensity we conclude that
with localisation, PCr is depleted to a lower level, recovery from depletion
is faster and no compartmentation of pH, manifest in a spliting of the Pi
peak is observed, in contrast to non-localised 31P MRS.