Ernesto Staroswiecki1,2, Kristin Lee
Granlund1,2, Marcus Tedrow Alley1, Garry Evan Gold1,
Brian Andrew Hargreaves1
1Radiology, Stanford University,
Stanford, CA, United States; 2Electrical Engineering, Stanford
University, Stanford, CA, United States
Detailed
visualization of articular cartilage is a challenge that requires advanced
MRI techniques. In order to detect early changes of osteoarthritis, we
require contrast mechanisms capable of showing biochemical properties of
cartilage like T2-mapping and diffusion-weighted-imaging. Here we study the
diffusion sensitivity of the T2 maps of cartilage generated with a DESS sequence,
and present a method for generating T2-weighted and diffusion-weighted
images, together with T2 maps and relative-ADC maps of cartilage via two
sequential DESS acquisitions with different gradient amplitudes.