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Abstract #0760

Varied Sampling Patterns in Modified Look-Locker with Saturation Recovery for Flexible Cardiac T1 Mapping

Ting Song1,2, Vincent B. Ho2,3, Glenn Slavin1, Maureen N. Hood2,3, Jeffrey A. Stainsby4

1GE Healthcare Applied Science Laboratory, Bethesda, MD, United States; 2Radiology, Uniformed Services University of the Health Sciences, Bethesda, MD, United States; 3Radiology, National Navy Medical Center, Bethesda, MD, United States; 4GE Healthcare Applied Science Laboratory, Toronto, ON, Canada


A cardiac T1 mapping sequence using a modified Look-Locker with saturation recovery acquisition provides increased flexibility with respect to sampling of the signal recovery curve over more traditional inversion recovery T1 mapping methods. In this work we explore different sampling patterns on phantoms and human subjects. A sampling scheme requiring half the data samples and thus half the breath hold time is compared to previous methods. An SNR sensitivity analysis was performed to confirm the accuracy of the reduced data sampling method at clinically relevant SNR and tissue T1 values.