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Abstract #0733

Assessment of Melanoma Extent and Melanoma Metastases Invasion Using Electron Paramagnetic Resonance and Bioluminescence Imaging

Quentin Godechal1, Florence Defresne2, Philippe Leveque1, Jean-Franois Baurain3, Olivier Feron2, Bernard Gallez1

1Biomedical Magnetic Resonance Unit, Universit Catholique de Louvain, Bruxelles, Belgium; 2Pharmacotherapy Unit, Universit Catholique de Louvain, Bruxelles, Belgium; 3Medical Oncology Unit, Universit Catholique de Louvain, Bruxelles, Belgium


Malignant melanoma is a skin tumor characterized by the uncontrolled proliferation of melanocytes, which can lead to metastasis mainly in lungs. The incidence of melanoma is rising each year. For this reason, it is essential to develop new effective methods able to detect melanoma. The purpose of the present study is to assess the ability of EPR to detect and measure the colonization of lungs by melanoma metastases. Results will be compared to results obtained with bioluminescence imaging in order to validate the EPR method.