Jinsoo Uh1, Ai-Ling Lin2, Kihak
Lee2, Peter Fox2, Hanzhang Lu1
1Advanced Imaging Research Center,
University of Texas Southwestern Medical Center, Dallas, TX, United States; 2Research
Imaging Institute, University of Texas Health Science Center, San Antonio,
TX, United States
This
study validates the use of VASO-MRI for quantitative measurement of cerebral
blood volume in unit of ml blood in 100 ml brain. We measured CBV values
using PET and VASO-MRI on the same subjects and compared them. The results
showed that VASO-MRI provides quantitative and accurate estimations of CBV
values in the human brain. Our data also demonstrated that VASO CBV has a
higher SNR compared to the PET technique in addition to providing a higher
spatial resolution.