Kristin L. Granlund1,2, Ernesto Staroswiecki1,2,
Marcus T. Alley1, Bruce L. Daniel1, Brian A. Hargreaves1
1Radiology, Stanford University,
Stanford, CA, United States; 2Electrical Engineering, Stanford
University, Stanford, CA, United States
High
resolution breast MRI is useful for distinguishing benign and malignant
tumors. The FADE sequence allows us to
acquire two images during a single scan with different image contrasts, the
first image having high SNR and the second image having T2 weighting. A second pair of images can then be
acquired with different crusher areas to evaluate the diffusivity of
different tissues. Phantom studies
were performed to confirm sources of image contrast. The technique was then evaluated in two
patients and it was found that the FADE sequence highlighted tumors with both
high T2 and restricted diffusion.