Fat-Referenced MR Thermometry in Heterogeneous Tissue Using IDEAL

Lorne Hofstetter¹, Desmond Teck Beng Yeo², Cynthia Davis², Thomas K. Foo²

Time-varying, non-temperature dependent phase changes affect the accuracy of conventional phase difference proton resonance frequency shift (PRFS) temperature mapping in the breast. We demonstrate a fat-referenced PRFS technique capable of correcting for this phase variation. This new approach reduced temperature measurement error in the left breast by a factor of 3.6 and in the right breast by a factor of 2.5 when compared to conventional phase difference techniques (n = 1).