Martin
Krssak1,2, Yvonne Winhofer2, Christian Gbl2,
Martin Bischof2, Gert Reiter3, Alexandra Kautzky-Willer2,
Anton Luger2, Michael Krebs2, Christian Anderwald2
1Radiology, Medical University of
Vienna, Wien, Austria; 2Internal Medicine III, Medical University
of Vienna, Wien, Austria; 3Siemens Healthcare Austria, Graz,
Austria
Myocardial
lipid accumulation and myocardial function were measured by 1H MR
spectroscopy and imaging in a group of non-diabetic insulin sensitive and
metabolically matched non-diabetic insulin resistant women. No differences
were found between these two groups, but hampered myocardial function and
increased myocardial lipid accumulation was found in a group patients with
type 2 diabetic mellitus, who served as a negative controls. Our results
suggest that increased myocardial lipid content and restricted myocardial
capacity are not linked to insulin resistance per se, but might develop after
the manifestation of type-2 diabetes.