Chia-Ying Liu1, Alban Redheuil1,
Ronald Ouwerkerk2, Charles Steenbergen3, Shenghan Lai4,
Joao Lima1, David Bluemke5
1Department of Radiology, Johns Hopkins
Hospital, Baltimore, MD, United States; 2The National Institute of
Diabetes and Digestive and Kidney Diseases, National Institutes of Health,
Bethesda, MD, United States; 3Department of Pathology, The Johns
Hopkins University, Baltimore, MD, United States; 4Department of
Epidemiology, Johns Hopkins School of Hygiene and Public health, Baltimore,
MD, United States; 5Radiology and Imaging Sciences, National
Institutes of Health, Bethesda, MD, United States
The
concept of fat contained within the myocardium, has recently received attention
because of its potential role in diabetic myocardial disease, obesity, and
HIV infected individuals. Measurements of myocardial triglycerides in humans
have been accessed using proton MR spectroscopy (1H MRS). We studied the
accuracy of the dual-echo Dixon MRI in quantifying the fatty content of the
myocardium in autopsies and patients. 1H MRS as an independent method was
also applied for comparison.