Li An1, Steven Warach1, Jun Shen2
1National Institute of Neurological
Disorders and Stroke, National Institutes of Health,
This
work demonstrates a new method that allows multi-compartmental spatial
localization based on the heterogeneity of sensitivity profiles of phased
array receiver coils. This method
offers an alternative to SENSE-CSI for performing spectroscopy using phased
array coils. It allows the user to manually prescribe compartments following
natural anatomical or physiological boundaries to reduce partial volume
artifacts associated with conventional CSI and SENSE-CSI. In vivo application
using PRESS and an eight-element phased array head coil demonstrates that
this method can extract spectra from stroke tissue and normal tissue in 4
seconds.