Kuang-Chi
Tung1, Jinsoo Uh1, Hanzhang Lu1
1Advanced Imaging Research Center, University
of Texas Southwestern Medical Center, Dallas, TX, United States
We
hypothesized that an important feature of the evoked activity, the plasticity
of the neural response, may also be present in the resting condition and may
provide critical information for understanding the nature and significance of
the resting state brain activity. Using motor cortex as a model, we
demonstrated for the first time that the resting brain activity can be
altered after repetitive stimulation of the associated brain networks. This
method may provide a new approach to study brain plasticity in humans and may
find applications in studies of aging and neurodegenerative diseases.