Allen W. Song1, Nan-Kuei Chen1, Brian Soher2
1Brain Imaging and Analysis Center, Duke
University, Durham, NC, USA; 2Radiology, Duke University, Durham,
NC, USA
In this report we aim to achieve a uniform and targeted spatial excitation
under Bo inhomogeneity. Specifically, we use fat suppression as an example to
demonstrate a new strategy termed Bo anchored spatial excitation (BASE), where
the transmit frequencies of individual channels are matched to those of the
local regions under an inhomogeneous magnetic field. We show that this approach
can effectively overcome the field inhomogeneities, and greatly reduce the
off-resonance effects during excitation. It is hoped that this new BASE
technique can find wide applications in imaging and spectroscopy in vivo in the
presence of large field inhomogeneities.