Thomas G. Perkins1, Julien Sngas2, Hannes Dahnke2, Elliot Sandberg3,4, William W. Orrison5,6
1Philips Healthcare, Cleveland, OH, USA; 2Philips Research Europe, Hamburg, Germany; 3Department of Radiology, VAMC, Denver, CO, USA; 4Departments of Radiology and Neurology, University of Colorado Health Science Center, Aurora, CO, USA; 5Nevada Imaging Centers, Las Vegas, NV, USA; 6Touro University Nevada College of Osteopathic Medicine, Henderson, NV, USA
Positive contrast imaging based on susceptibility gradient mapping (SGM) is a relatively new technique that produces maps with high contrast-to-noise ratio for areas of local magnetic susceptibility variation. Applying high resolution SGM to assess localized abnormalities associated with hemosiderin deposition in conditions such as traumatic brain injury or cavernous angiomas could provide additional clinical information for detection and diagnosis. The purpose of this study was to explore the potential clinical utility of SGM to provide better characterization of cavernous angiomas, and shows the potential utility of positive contrast imaging for the visualization of localized vascular abnormalities.