Deconvolution and QSI of Simulated Phase Images of the Human Brain: Applications to Assess Susceptibility

Guenther Grabner^1,2, Siegfried Trattnig¹, Markus Barth²

MR phase images reflect the magnetic susceptibility of tissues but the phase image is a convolution of the susceptibility map with the typical pattern of magnetic dipole. This leads to very complex phase patterns in areas of differing susceptibility. The challenge is to estimate the underlying tissue susceptibilities. We wanted to assess how accurate the underlying properties can be determined by performing filtered deconvolution and QSI on a simulated phase model.