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Abstract #4289

Enhanced In-Vivo C13 Spectroscopy Using Adiabatic INEPT Sequences and Custom-Made RF Coils

Ovidiu C. Andronesi1, Dionyssios Mintzopoulos1,2, Hellmut Merkle3, A Aria Tzika1,2

1Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Boston, MA, USA; 2NMR Surgical Laboratory, MGH & Shriners Hospitals, Harvard Medical School, Boston, MA, USA; 3National Institutes of Health, Laboratory of Functional and Molecular Imaging, Bethesda, MD, USA


We report significant C13 spectroscopic signal enhancement in vivo using an optimized adiabatic INEPT sequence (BINEPT, with BIR-4 pulses) and a custom-made high-quality RF coil, at high field (9.4 T).