Satoru Kitano1, Nagaaki Marugami1, Junko Takahama1, Aya Hashimoto1, toshiaki Taoka1, shinji Hirohashi2, kimihiko Kichikawa1
1Department of Radiology, Nara Medical University, kashihara, Nara, Japan; 2Department of Radiology, osaka gyoumeikan hospital, osaka, Japan
Gd-EOB-DTPA is a new hepatobiliary MRI contrast agent, detection and characterization of liver tumors. This compound is taken up by the hepatocytes and is equally excreted renal and biliary in humans. Dynamic and accumulation phase imaging can also be performed after bolus injection of Gd-EOB-DTPA. Time-resolved MR angiography (MRA) offers the combined advantage of large anatomic coverage and hemodynamic flow information. We applied parallel imaging and time-resolved imaging with stochastic trajectories (TWIST) to perform Gd-EOB-DTPA enhanced dynamic MRI for hepatocellular carcinoma. We obtained quintuple arterial phase dynamic MR imaging and time resolved MR angiography simultaneously. The purpose of this study was to describe and validate the use of time resolved Gd-EOB-DTPA enhanced MRI for the noninvasive assessment of hemodynamics and hepatocytes functional information of hypervascular hepatocellular carcinoma.