Marcus Carlsson1,2, Demetrius Dicks1, Einar Heiberg2, Alastair Martin1, David Saloner1, Hakan Arheden2, Maythem Saeed1
1UCSF, Dep of Radiology and Biomedical Imaging, San Francisco, CA, USA; 2Lund University Hospital, Dep of Clinical Physiology, Lund, Sweden
This MRI study determined the ability of phase velocity encoded (PC-MR) strain to detect the functional effects on left ventricular radial and longitudinal strain after microembolization in the LAD coronary artery in an animal model. PC-MR imaging was sensitive to dectect the changes in longitudinal and radial strain after selective LAD coronary embolization. Longitudinal strain of the patchy microinfarction declined from baseline to 1-hour after embolization, a decline that persisted at 1 week. Radial strain declined acutely 1-hour after LAD embolization and worsened at 1 week post-embolization.