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Abstract #3791

Quantification of 3-Directional Motion of Papillary Muscle Using Tissue Velocity Mapping in Patients with Mitral Valve Prolapse

Yuchi Han1, Kraig V. Kissinger1, Beth Goddu1, Warren J. Manning1,2, Reza Nezafat1

1Medicine/Cardiology, BIDMC/Harvard Medical School, Boston, MA, USA; 2Radiology, BIDMC/Harvard Medical School, Boston, MA, USA


In patients with mitral valve prolapse, the tension exerted by the thickened and enlongated mitral leaflets on the papillary muscle during systole may be important in understanding mitral regurgitation progression and the generation of papillary muscle fibrosis. We sought to investigate the feasibility of high spatial and temporal resolution MR phase contrast technique to investigate the 3D motion of papillary muscle and its velocity in MVP patient as well as healthy subjects.