Jrgen Finsterbusch1,2
1Dept. of Systems Neuroscience,
University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2Neuroimage Nord, Hamburg-Kiel-Lbeck, Germany
An extension of the double wave vector diffusion-weighting experiment with
short mixing time that involves multiple concatenations of the two
diffusion-weighting periods in a single experiment is proposed. A generalized
tensor model is presented to describe the signal behaviour for arbitrary
orientation distributions and number of concatenations. The absolute and
relative signal modulation increases with the number of concatenations
approaching twice the value observed for the un-concatenated experiment. Thus,
multiple concatenations may help to improve the detectability of the signal
modulation on whole-body MR systems. These results are confirmed by numerical
simulations using a Monte-Carlo algorithm.