Robert Vincent Mulkern1, Richard Lee Robertson1, Stephen John Haker2, Dimitrios Mitsouras2, Stephan E. Maier2
1Radiology, Children's Hospital, Boston, MA, USA; 2Radiology, Brigham and Women's Hospital, Boston, MA, USA
The dependence of biexponential parameters characterizing diffusion decay curves from the splenium on the angle between fiber direction and diffusion sensitization direction was examined. An angular dependence of the slow diffusion coefficient consistent with current models was obtained. A similar angular dependence for the fast fraction amplitude and the fast diffusion coefficient was also found, features which are not explained by current models.