Silvia De Santis1,2, Silvia Capuani3
1Physics Department Sapienza University Rome, Rome, Italy; 2CNR-INFM SOFT , Physics Department Sapienza University Rome, Rome, Italy; 3CNR-INFM SOFT, Physics Department Sapienza University Rome, Rome, Italy
Our goal was to investigate the potential role of non-gaussian diffusion methods in discriminating among the different cerebral tissues (i.e. WM, GW, CSF) and in detecting differences into a selected tissue characterized by a known MR-parameter. This preliminary study shows a different pattern of values when considering WM and GM tissues. Moreover, a different pattern of change is detectable for WM regions with a higher (i.e., corpus-callosum) as compared to those with a lower level of fiber tracts coherency (i.e., corona radiata). values might be suitable for detecting subtle changes in neurological disorders not associated with macroscopic tissue-damages.