Adrian Tsang1, Rob Stobbe1, Ken Butcher2, Shazam Hussain, Yusuf Bhagat1, Derek Emery3, Christian Beaulieu1
1Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada; 2Neurology, University of Alberta, Edmonton, Alberta, Canada; 3Radiology, University of Alberta, Edmonton, Alberta, Canada
Sodium imaging may complement both diffusion- and perfusion-weighted proton imaging in the assessment of ischemic stroke patients. The purpose of this study is to evaluate the relative tissue sodium intensity in the penumbra defined by PWI-DWI mismatch and core infarct regions defined by DWI from acute to subacute times. Preliminary results based on 4 longitudinal subjects demonstrated that mean relative sodium intensity increases with time only in the infarct core but does not change in the penumbra.