Hongyu An1, Andria L. Ford2, Katie Vo3, William J. Powers4, Jin-Moo Lee2, Weili Lin1
1Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; 2Neurology, Washington University in St. Louis, St. Louis, MO, USA; 3Radiology, Washington University in St. Louis, St. Louis, MO, USA; 4Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Temporal behavior of ADC lesions during hyperacute ischemia and the final fate of these lesions were examined in the presence or absence of reperfusion. ADC increased significantly after reperfusion, while it decreased slightly if reperfusion did not occur. Reversal of ADC abnormality within 3 to 6 hours after stroke does not necessarily reflect a recovery of ischemic tissue. Furthermore, a time lag was observed between the changes of perfusion and the changes of diffusion (both normalization and worsening).