Abstract #3262

qCBF: A Comparison of the Accuracy Between the Bookend Technique, Empirical Reference Values and [O15]-H20 PET in Moyamoya Patients

Vishal Parikh¹, John Lee², Wanyong Shin³, Jessy Mouannes¹, Avi Snyder², Colin Derdeyn^2,4, Timothy Carroll^1,5

¹Biomedical Engineering, Northwestern University, Evanston, IL, USA; ²Radiology, Washington University, St. Louis, MO, USA; ³National Institute of Health, Baltimore, MD, USA; ⁴Neurology, Washington University, St. Louis, MO, USA; ⁵Radiology, Northwestern University, Chicago, IL, USA

We compared the accuracy of CBF measurements obtained by the Bookend Technique and CBF values rescaled to 22mL/100g/min for white matter. The accuracy with respect to [¹⁵O]-H₂O positron emission tomography (PET) in patients with angiographically confirmed cerebrovascular disease. We found that the bookend approach provided a stronger correlation with the standard of reference PET values.