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Abstract #2508

Assessment of Hepatic Fibrosis in Liver Transplant Patients Using MR Elastography - Preliminary Results

Patrick Asbach1, Dieter Klatt1, Carsten Kamphues2, Peter Neuhaus2, Jrgen Braun3, Ingolf Sack1

1Department of Radiology, Charit University Hospital, Berlin, Germany; 2Department of General-, Visceral- and Transplantation Surgery, Charit University Hospital, Berlin, Germany; 3Department of Medical Informatics, Charit University Hospital, Berlin, Germany


Following liver transplantation viral re-infection of the graft frequently occurs and progression of fibrosis advances more quickly in the transplanted liver. The aim of the study was to investigate the potential of MR-elastography (MRE) in detecting liver fibrosis in transplant patients. MRE was applied to 10 patients with biopsy-proven liver fibrosis. Significant differences were found between the viscoelasticity of the liver of low-grade fibrosis patients ( = 3.21 0.27; mean SD) and high-grade fibrosis patients ( = 5.19 1.27). MR elastography has the potential to non-invasively detect liver fibrosis in transplant patients.